Ira Tabas Selected Research

MAP-kinase-activated kinase 2

1/2021	Allosteric MAPKAPK2 inhibitors improve plaque stability in advanced atherosclerosis.
10/2015	Treatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin Sensitivity.

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Ira Tabas Research Topics

Disease

62	Atherosclerosis 04/2022 - 04/2002
28	Inflammation (Inflammations) 01/2021 - 04/2002
18	Necrosis 01/2022 - 11/2002
16	Atherosclerotic Plaque (Atheroma) 01/2022 - 02/2004
12	Insulin Resistance 01/2021 - 11/2007
10	Obesity 01/2020 - 03/2004
8	Peritonitis 01/2022 - 04/2013
8	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 05/2006
7	Fibrosis (Cirrhosis) 01/2022 - 12/2016
6	Type 2 Diabetes Mellitus (MODY) 01/2018 - 11/2008
5	Thrombosis (Thrombus) 01/2020 - 11/2006
4	Non-alcoholic Fatty Liver Disease 01/2021 - 11/2018
4	Coronary Artery Disease (Coronary Atherosclerosis) 05/2012 - 08/2005
3	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2020
3	Myocardial Infarction 01/2021 - 03/2010
3	Hypercholesterolemia 01/2018 - 05/2005
3	Porcine Reproductive and Respiratory Syndrome (PRRS) 09/2009 - 12/2006
2	Pathologic Processes 04/2022 - 01/2017
2	Myocardial Ischemia (Ischemic Heart Diseases) 01/2021 - 09/2017
2	Infarction (Infarctions) 01/2021 - 09/2017
2	Disease Progression 01/2018 - 09/2009
2	Reperfusion Injury 09/2017 - 04/2013
2	Infections 01/2016 - 03/2014
2	Hyperglycemia 01/2016 - 10/2015
2	Hyperlipidemias (Hyperlipidemia) 02/2013 - 05/2008
2	Coronary Disease (Coronary Heart Disease) 03/2010 - 05/2006
2	Vascular Diseases (Vascular Disease) 01/2007 - 11/2006
2	Sitosterolemia 01/2007 - 11/2006
1	Neoplasms (Cancer) 04/2022
1	Liver Diseases (Liver Disease) 01/2022
1	Body Weight (Weight, Body) 01/2021
1	Alcoholic Fatty Liver 01/2020

Drug/Important Bio-Agent (IBA)

23	CholesterolIBA 01/2021 - 11/2002
15	Lipoproteins (Lipoprotein)IBA 10/2018 - 04/2002
14	c-Mer Tyrosine KinaseIBA 01/2022 - 08/2008
13	LipidsIBA 01/2020 - 02/2004
11	Insulin (Novolin)FDA Link 01/2016 - 03/2004
9	Proteins (Proteins, Gene)FDA Link 04/2022 - 12/2008
7	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2018 - 10/2009
6	CytokinesIBA 01/2021 - 04/2002
6	Apolipoproteins E (ApoE)IBA 05/2014 - 08/2008
5	ZymosanIBA 12/2021 - 04/2013
5	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 04/2012
5	Biological ProductsIBA 10/2018 - 11/2003
5	ApolipoproteinsIBA 10/2018 - 10/2007
4	Small Interfering RNA (siRNA)IBA 01/2022 - 01/2016
4	RNA (Ribonucleic Acid)IBA 01/2022 - 09/2019
4	LDL Receptors (LDL Receptor)IBA 03/2012 - 11/2003
4	Pattern Recognition ReceptorsIBA 09/2011 - 12/2006
3	EnzymesIBA 04/2022 - 09/2010
3	Triglycerides (Triacylglycerol)IBA 01/2021 - 03/2010
3	CollagenIBA 01/2018 - 04/2013
3	Apolipoproteins B (ApoB)IBA 02/2017 - 08/2005
3	Peptides (Polypeptides)IBA 02/2015 - 08/2005
3	LDL Lipoproteins (beta Lipoproteins)IBA 01/2015 - 04/2005
3	CalciumIBA 12/2013 - 05/2006
3	PPAR gammaIBA 06/2010 - 03/2004
2	Calcium-Calmodulin-Dependent Protein KinasesIBA 01/2022 - 12/2013
2	Interleukin-10 (Interleukin 10)IBA 01/2021 - 01/2016
2	PutrescineIBA 01/2021 - 01/2020
2	Antisense OligonucleotidesIBA 01/2021 - 11/2018
2	LigandsIBA 01/2021 - 06/2017
2	MAP-kinase-activated kinase 2IBA 01/2021 - 10/2015
2	LeukotrienesIBA 01/2019 - 09/2016
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2018 - 06/2017
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 09/2017 - 06/2016
2	Transcription Factor CHOPIBA 05/2015 - 09/2010
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2015 - 05/2014
2	Phosphotransferases (Kinase)IBA 12/2013 - 06/2005
2	Transcription Factors (Transcription Factor)IBA 03/2012 - 12/2011
2	SphingomyelinsIBA 03/2010 - 05/2006
2	Insulin ReceptorIBA 01/2010 - 04/2006
2	AcidsIBA 10/2008 - 04/2005
1	DNA (Deoxyribonucleic Acid)IBA 04/2022
1	8-hydroxyguanineIBA 04/2022
1	DNA Repair EnzymesIBA 04/2022
1	NADP (NADPH)IBA 04/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022
1	Dinoprostone (PGE2)FDA Link 01/2022
1	Platelet-Derived Growth FactorIBA 01/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2021
1	nasIBA 01/2021
1	Sucrose (Saccharose)IBA 01/2021
1	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 01/2021
1	Mitogen-Activated Protein KinasesIBA 01/2021
1	PalmitatesIBA 01/2021
1	Axl Receptor Tyrosine KinaseIBA 01/2021
1	AcetylgalactosamineIBA 01/2021
1	Plasminogen Activator Inhibitor 1IBA 01/2020
1	Metalloproteases (Metalloproteinases)IBA 01/2020
1	PlasticsIBA 01/2020
1	Transcriptional Coactivator with PDZ-Binding Motif ProteinsIBA 09/2019
1	Co-Repressor ProteinsIBA 01/2019
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2019
1	Arachidonic Acid (Vitamin F)IBA 01/2019
1	OsteopontinIBA 11/2018
1	LipopolysaccharidesIBA 10/2018

Therapy/Procedure

14	Therapeutics 04/2022 - 10/2007
2	Drug Therapy (Chemotherapy) 01/2021 - 11/2018
1	Glycemic Control 01/2020